autologous stem cell transplant procedure

There are several sources of stem cell donors for allogeneic stem cell/bone marrow transplant patients, including: What are the possible sources of donor stem cells for allogeneic transplant? With the amount of cancerous tissue reduced, the transplanted stem cells produce millions of healthy white blood cells, which mount anĪttack on the remaining cancer cells - a phenomenon known as the graft-versus-leukemia effect. Kill some of the tumor cells, that is not the goal of the chemotherapy given prior to the transplant. A reduced-intensity (or 'mini' or 'RIC') allogeneic transplant uses a reduced amount of chemotherapy to suppress the patient's immune system enough so that the donor stem cells can take root, or 'engraft,' there.A myeloablative transplant uses large doses of chemotherapy - or a combination of chemotherapy and radiation – to overcome resistance and eradicate a patient's malignancy.There are two main types of allogeneic transplants: The stem cell donor may be related to the patient or may be an unrelated volunteer found through aĭonor registry such as the National Marrow Donor Program. An allogeneic transplant uses stem cells from a donor whose human leukocyte antigens (HLA) are acceptable matches to the patient's.It will help patients prepare for their peripheral blood stem cell collection (PBSC), in which their own stem cells are collected and returned to after receiving conditioning chemotherapy. This video provides an overview of the stem cell collection process for autologous stem cell transplant patients. The Stem Cell Collection Process for Autologous Stem Cell Transplant Patients To the body to help it produce healthy red and white blood cells and platelets.

Following conditioning treatment, the patient's stem cells are returned Stem cells are collected from the patient and frozen in liquid nitrogen before transplant conditioning.

An autologous transplant uses a patient's own stem cells.

Your physician will decide what type of transplant should be used for your treatment and the source of the stem cells: There are two main types of stem cell/bone marrow transplant. What are the types of stem cell/bone marrow transplant?

You have a disease that is treated with high doses of chemotherapy and/or radiation treatment, which destroys both cancerous and stem cells at the same time.Your bone marrow or blood cells have become diseased and need to be replaced.Your body cannot make the blood cells it needs because your bone marrow or stem cells have failed.You may need a stem cell/bone marrow transplant when: When is a stem cell/bone marrow transplant needed? You may hear the procedure referred to as a bone marrow transplant (BMT), or a peripheral blood stem cell transplant (PBSCT), or an umbilical cord blood transplantation (UCBT), depending on the source of the stem cells that are used. They form white blood cells (which fight infections), red blood cells (which carry oxygen throughout the body), and platelets (which allow blood to clot, helping wounds heal) - all the components your immune system needs to function.ĭuring a transplant, healthy stem cells are transplanted from one individual to another or using an individual's own stem cells to grow and produce all of the different parts of the blood that both your body and your immune system need. Stem cells are the 'building blocks' of bone marrow and blood formation. Stem cell/bone marrow transplant offers some patients with benign and hematologic diseases the possibility of a cure, and others a longer period of disease-free survival. What is a stem cell/bone marrow transplant?

Autologous stem cell transplant procedure